Imaging and MR Spectroscopy in Papillary Craniopharyngioma
Case studies
Ashima Mahajan
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Bheru Dan Charan
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Sushant Agarwal
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Vinay Goel
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Leve Joseph Devarajan Sebastian
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Vaishali Suri
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
Ashish Suri
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India
Ajay Garg
Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Published 2024-05-22
https://doi.org/10.15388/Amed.2024.31.1.10
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Keywords

Craniopharyngioma
Spectroscopy
Suprasellar

How to Cite

1.
Mahajan A, Bheru Dan Charan, Sushant Agarwal, Vinay Goel, Devarajan Sebastian LJ, Suri V, et al. Imaging and MR Spectroscopy in Papillary Craniopharyngioma. AML [Internet]. 2024 May 22 [cited 2024 Nov. 21];31(1):157-63. Available from: https://journals.vu.lt./AML/article/view/33771

Abstract

Sellar-suprasellar masses exhibit a diverse range of differential diagnoses and it is feasible to establish a preliminary diagnosis before surgery by evaluating conventional CT scans and contrast-enhanced MRI results. Nevertheless, certain cases may present with inconclusive findings, making it challenging to anticipate the underlying tissue composition accurately through imaging alone. Researchers have explored the application of Proton MR spectroscopy in analyzing suprasellar tumors, and their investigations have revealed that it can complement traditional MRI by enhancing the accuracy of preoperative diagnoses. In this context, we report three biopsy-proven cases of suprasellar papillary craniopharyngioma where the MRS spectra derived from the solid component exhibited noticeable lipid peaks alongside reduced levels of choline and NAA. These findings played a pivotal role in facilitating the correct preoperative identification of papillary craniopharyngioma.

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